A Prospective Observational Study on Prevalence of Anemia, Associated Risk Factors and Outcome

Phocas Havugimana, Raphael Ndahimana, Felix Babane, Ernestine Umutesi, Polyphile Ntihinyurwa, Diane Mushimiyimana, Florence Masaisa, Etienne Ntabanganyimana

Abstract


Background: Admitted patients with anemia are at increased morbidity and mortality risk, as well as length of hospital stay. It affects more than 2 billion people worldwide and is causing significant morbidity and mortality. Its etiology is variable, with many predisposing factors including nutritional deficiencies, infections, malignancies, chronic inflammations, and other chronic diseases like autoimmune diseases, chronic liver disease, and chronic kidney disease. Methods: We performed a non-randomized, prospective observational study of 143 patients admitted to internal medicine between March and April 2021 and assessed their hemoglobin level in order to determine the prevalence of anemia. The demographic and clinical data were collected using a specially designed questionnaire. All patients found to have anemia were followed for outcome assessment (either discharge or death). Results: The prevalence of anemia was high (52.4%) among the 143 admitted patients in internal medicine at CHUK. Patients with HIV, cancer, and chronic kidney disease had a 5.84-, 4.11-, and 3.79-times higher risk of having anemia, respectively. In 75 patients who had anemia, 10 patients died; among them, 5 patients had severe anemia; 25 patients were 60 years old and above; 60 patients had normocytic anemia, and they had an average length of hospital stay of 20.6 days; for patients with severe anemia, the length of hospital stay was 28 days. Conclusion: This study demonstrated a high prevalence of anemia, which is associated with a high mortality rate among admitted patients in CHUK. Priority should be given to preventive medicine, optimal management of chronic disease, and geriatric medicine.

 

Doi: 10.28991/SciMedJ-2022-04-02-05

Full Text: PDF


Keywords


Hospitalized Patients; Anemia in CHUK; Prevalence of Anemia; Rwanda.

References


Bisht, N., Sofia, Dr., & Neki, N. S. (2017). Prevalence and pattern of anemia in elderly- A hospital based study. International Journal of Current Research in Medical Sciences, 3(6), 27–35. doi:10.22192/ijcrms.2017.03.06.004.

Farhat, B., Ayesha, N., Saera, K., Shahdil, Z., Sehar, S., & Jamal, A. (2017). Anemia in hospitalized patient: Prevalence, etiology and risk factors. Journal of Liaquat University of Medical & Health Sciences, 16(02), 80–85. doi:10.22442/jlumhs.171620511.

Obaidely, M. A., Nadukkandiyil, N., Asim, M., Najma, F. A., Hamad, H. A., & Sulaiti, E. A. (2017). Prevalence and Impact of Anemia among Elderly Population in Qatar: A Cross Sectional Study. Journal of Gerontology & Geriatric Research, 06(03), 1000421. doi:10.4172/2167-7182.1000421.

Simbauranga, R. H., Kamugisha, E., Hokororo, A., Kidenya, B. R., & Makani, J. (2015). Prevalence and factors associated with severe anaemia amongst under-five children hospitalized at Bugando Medical Centre, Mwanza, Tanzania. BMC Hematology, 15(1), 2-9. doi:10.1186/s12878-015-0033-5.

Chatterjee, P. (2018). A study of prevalence of anemia along with its diagnosis and treatment. Hematology & Transfusion International Journal, 6(2), 84-87. doi:10.15406/htij.2018.06.00158.

Mengesha, M. B., & Dadi, G. B. (2019). Prevalence of anemia among adults at Hawassa University referral hospital, Southern Ethiopia. BMC Hematology, 19(1), 1-7. doi:10.1186/s12878-018-0133-0.

Enawgaw, B., Workineh, Y., Tadesse, S., Mekuria, E., Addisu, A., & Genetu, M. (2019). Prevalence of anemia and associated factors among hospitalized children attending the University of Gondar Hospital, Northwest Ethiopia. EJIFCC, 30(1), 35.

Zekarias, B., Meleko, A., Hayder, A., Nigatu, A., & Yetagessu, T. (2017). Prevalence of Anemia and its Associated Factors among Pregnant Women Attending Antenatal Care (ANC) In Mizan Tepi University Teaching Hospital, South West Ethiopia. Health Science Journal, 11(5), 1-8. doi:10.21767/1791-809x.1000529.

Makubi, A., Hage, C., Lwakatare, J., Mmbando, B., Kisenge, P., Lund, L. H., Rydén, L., & Makani, J. (2014). Prevalence and prognostic implications of anaemia and iron deficiency in Tanzanian patients with heart failure. Heart, 101(8), 592–599. doi:10.1136/heartjnl-2014-306890.

De Benoist, B., Cogswell, M., Egli, I., & McLean, E. (2008). Worldwide prevalence of anaemia 1993-2005; WHO Global Database of anaemia. World Health Organization (WHO), Geneva, Switzerland.

Raza, S., Wei, J., Ashad Abid, S., & Azhar, G. (2014). Are Blood Transfusions Useful for Non-Specific Symptoms of Anemia in the Elderly? Open Medicine Journal, 1(1), 36–49. doi:10.2174/1874220301401010036.

Makam, A. N., Nguyen, O. K., Clark, C., & Halm, E. A. (2017). Incidence, Predictors, and Outcomes of Hospitalâ€Acquired Anemia. Journal of Hospital Medicine, 12(5), 317–322. doi:10.12788/jhm.2723.

Dunlay, S. M., Weston, S. A., Redfield, M. M., Killian, J. M., & Roger, V. L. (2008). Anemia and Heart Failure: A Community Study. The American Journal of Medicine, 121(8), 726–732. doi:10.1016/j.amjmed.2008.03.039.

Sirbu, O. (2018). Anemia in heart failure - from guidelines to controversies and challenges. The Anatolian Journal of Cardiology. doi:10.14744/anatoljcardiol.2018.08634.

National Institute of Statistics of Rwanda (NISR). (2015). Rwanda Demographic Health Survey 2014-2015. Ministry of Health (MOH) [Rwanda] and ICF International, Rockville, United States.

Rachoin, J.-S., Cerceo, E., Milcarek, B., Hunter, K., & Gerber, D. R. (2013). Prevalence and Impact of Anemia in Hospitalized Patients. Southern Medical Journal, 106(3), 202–206. doi:10.1097/smj.0b013e318287fcd9.

Culleton, B. F., Manns, B. J., Zhang, J., Tonelli, M., Klarenbach, S., & Hemmelgarn, B. R. (2006). Impact of anemia on hospitalization and mortality in older adults. Blood, 107(10), 3841–3846. doi:10.1182/blood-2005-10-4308.

Zaninetti, C., Klersy, C., Scavariello, C., Bastia, R., Balduini, C. L., & Invernizzi, R. (2018). Prevalence of anemia in hospitalized internal medicine patients: Correlations with comorbidities and length of hospital stay. European Journal of Internal Medicine, 51, 11–17. doi:10.1016/j.ejim.2017.11.001.

Randi, M. L., Bertozzi, I., Santarossa, C., Cosi, E., Lucente, F., Bogoni, G., Biagetti, G., & Fabris, F. (2020). Prevalence and Causes of Anemia in Hospitalized Patients: Impact on Diseases Outcome. Journal of Clinical Medicine, 9(4), 950. doi:10.3390/jcm9040950.


Full Text: PDF

DOI: 10.28991/SciMedJ-2022-04-02-05

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Etienne Ntabanganyimana, Phocas Havugimana, Raphael Ndahimana, Felix Babane, Ernestine Umutesi, Polyphile Ntihinyurwa, Diane Mushimiyimana, Florence Masaisa