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  2. Vol 5, No 2 (2023)
  3. Osei-Boakye

Effect of Season on Blood Transfusion Patterns: A Retrospective Study

Felix Osei-Boakye, Nicholas Agyepong, Charles Nkansah, Abdul-Razak Saasi, Dorcas Serwaa, Mark Danquah, Kwesi Kattah, Mohammed Khadija, Fati Salifu, Andrea Owusu Antwi

Abstract


Background: Different seasons present varied environmental factors that influence the occurrence of transfusion-driven diseases. Therefore, this study determined the patterns of blood transfusion among hospitalized patients and the effect of season on ABO/Rh phenotypes. Methods: A single-center retrospective cross-sectional study was conducted on 5089 hospitalized patients that were transfused with blood at Sunyani Municipal Hospital. Archived blood transfusion records were retrieved and analyzed using GraphPad Prism, and SPSS. The association, effect size, and yearly trends of transfusion patterns were determined. Results: The majority of the participants were females (63.0% [3208]), 36-49 years old (20.4% [1039]), O phenotype (48.1% [2447]), Rh-positive (93.1% [4737]), and transfused in the rainy season (61.0% [3103]). Patients’ ABO was weakly associated with age (r = 0.07, p≤0.001) and season (r = 0.05, p = 0.008). Eighty percent (4053/5089) of the transfusions were ABO group-specific, and 28.3% (1146/4053) of this occurred at the emergency ward. The source of transfusion request was weakly associated with season (r = 0.1, p≤0.001) and type of transfusion (r = 0.1, p = 0.002). The rainy season (slope: 142.9, p≤0.001) and ABO-specific transfusions (slope: 219.5, p≤0.001) showed consistent increasing trends over the years. Conclusion: Blood transfusion was frequent among females, adults, Rh-positive and O phenotypes, and in the rainy season. Age and season were significantly associated with ABO, but not Rh. A transfusion request was associated with the season and type of transfusion, with the majority of transfusions occurring in the rainy season and emergency ward. There was an increasing yearly trend in blood transfusions.

 

Doi: 10.28991/SciMedJ-2023-05-02-03

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Keywords


Blood Transfusion; Inpatient; Rainfall; Season; Transfusion Pattern.

References


Ayede, A., & Akingbola, T. (2011). Pattern, indications and review of complications of neonatal blood transfusion in Ibadan, southwest Nigeria. Annals of Ibadan Postgraduate Medicine, 9(1), 30–36. doi:10.4314/aipm.v9i1.72432.

Abdoul-Samadou, A., Baguilane, D., Akila, B., Dédé, R. D. A., Kossi-Edem, L.-A., Kokou, D., Tchin, D., & Koffi, A. (2019). Blood Transfusion Practices at the Gynecology-Obstetrics Department of the Sylvanus Olympio University Hospital in Lome: A Study of 254 Cases. Open Journal of Obstetrics and Gynecology, 09(04), 494–501. doi:10.4236/ojog.2019.94048.

Al-Saqladi, A. W. M., Maddi, D. M., & Al-Sadeeq, A. H. (2020). Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease. Anemia, 2020. doi:10.1155/2020/7080264.

Raykar, N. P., Makin, J., Khajanchi, M., Olayo, B., Munoz Valencia, A., Roy, N., Ottolino, P., Zinco, A., MacLeod, J., Yazer, M., Rajgopal, J., Zeng, B., Lee, H. K., Bidanda, B., Kumar, P., Puyana, J. C., & Rudd, K. (2021). Assessing the global burden of hemorrhage: The global blood supply, deficits, and potential solutions. SAGE Open Medicine, 9, 1–11. doi:10.1177/20503121211054995.

Beyer, A., Rees, R., Palmer, C., Wessman, B. T., & Fuller, B. M. (2017). Blood product transfusion in emergency department patients: a case-control study of practice patterns and impact on outcome. International Journal of Emergency Medicine, 10(1), 5. doi:10.1186/s12245-017-0133-z.

Feyisa, T., Kiya, G. T., & Maleko, W. A. (2021). Assessment of recipients’ characteristics, transfusion appropriateness, and utilization pattern of blood and blood products in Jimma Medical Center, Jimma, Ethiopia. PLoS ONE, 16(4), 250623. doi:10.1371/journal.pone.0250623.

Bruun-Rasmussen, P., Kragh Andersen, P., Banasik, K., Brunak, S., & Johansson, P. I. (2022). Intervening on the storage time of RBC units and its effects on adverse recipient outcomes using real-world data. Blood, 139(25), 3647–3654. doi:10.1182/blood.2022015892.

Osaro, E., & Adias, T. (2011). The challenges of meeting the blood transfusion requirements in Sub-Saharan Africa: the need for the development of alternatives to allogenic blood. Journal of Blood Medicine, 2, 7. doi:10.2147/jbm.s17194.

Shohat, N., Ludwick, L., Goh, G. S., Sherman, M., Paladino, J., & Parvizi, J. (2021). Blood transfusions increase the risk for venous thromboembolism events following total joint arthroplasty. Scientific Reports, 11(1), 21240. doi:10.1038/s41598-021-00263-0.

Abbaszadeh Afshar, M. J., Raeesi Nejad, F., & Behzadi, A. (2021). Blood ordering and transfusion pattern: A retrospective monitoring of seven healthcare institutions in Southern Kerman province, Iran. Iranian Journal of Blood and Cancer, 13(1), 17–21.

Fall, P., Diouf, I., Deme, A., & Sene, D. (2022). Assessment of Climate-Driven Variations in Malaria Transmission in Senegal Using the VECTRI Model. Atmosphere, 13(3), 418. doi:10.3390/atmos13030418.

Sulemana, A., & Dinye, R. D. (2014). Access to healthcare in rural communities in Ghana: A study of some selected communities in the Pru district. European Journal of Research in Social Sciences, 2(4), 122–132.

Gyedu, A., Goodman, S. K., Quansah, R., Osei-Ampofo, M., Donkor, P., & Mock, C. (2021). Assessing the appropriateness of blood transfusion among injured patients at a Ghanaian tertiary hospital: Time for clarity on the use of a scarce resource. Injury, 52(5), 1164–1169. doi:10.1016/j.injury.2021.01.028.

Doku, G. N., Agbozo, W. K., Annor, R. A., Mawudzro, P. E., & Agbeli, E. E. (2022). Frequencies and ethnic distribution of ABO and RhD blood groups in the Volta region of Ghana, towards effective blood bank services. African Health Sciences, 22(1), 641–647. doi:10.4314/ahs.v22i1.74.

Doku, G. N., Agbozo, W. K., Annor, R. A., Kisseh, G. D., & Owusu, M. A. (2019). Frequency of ABO/Rhesus (D) blood groupings and ethnic distribution in the Greater-Accra region of Ghana, towards effective blood bank inventory. International Journal of Immunogenetics, 46(2), 67–73. doi:10.1111/iji.12412.

Osei-Boakye, F., Nkansah, C., Appiah, S. K., Derigubah, C. A., Mensah, K., Apandago, A. A., Boateng, V. A., Norsi, O. G., & Kogh-Nuu, D. (2023). Seroprevalence, trends, and risk factors of hepatitis B and C among family replacement blood donors; a 7-year retrospective study at Sunyani Municipal Hospital, Ghana. Journal of Immunoassay and Immunochemistry, 44(2), 162–175. doi:10.1080/15321819.2023.2168555.

Murphy, W. G. (2014). The sex difference in haemoglobin levels in adults - Mechanisms, causes, and consequences. Blood Reviews, 28(2), 41–47. doi:10.1016/j.blre.2013.12.003.

Kurup, A., Jha, A., Sahu, S., Sindhu, K. N. C., Bhatt, A., & Oommen, A. (2016). Voluntary blood donation in a rural block of Vellore, South India: A knowledge, attitude and practice study. CHRISMED Journal of Health and Research, 3(2), 123. doi:10.4103/2348-3334.177638.

Okuneye, K., Eikenberry, S. E., & Gumel, A. B. (2019). Weather-driven malaria transmission model with gonotrophic and sporogonic cycles. Journal of Biological Dynamics, 13(sup1), 288–324. doi:10.1080/17513758.2019.1570363.

Farshori, M. P. Q., Al-Wakid, I. H., Ibrahim, I. K. A., ALShammari, A. F., Alduejieman, M., Almhanaa, A. M., ... & Al-Muzaini, A. Y. (2016). Distribution of ABO and Rhesus (Rh) blood group antigens in male type 2 diabetes mellitus patients in Hail region of Saudi Arabia: High incidences of diabetes mellitus in males with B+ blood type. Integr Obesity Diabetes, 2(3), 233-238. doi:10.15761/IOD.1000151.

Nkansah, C., Serwaa, D., Osei-Boakye, F., & Owusu-Ampomah, R. (2022). Magnitude and trend of HIV and Treponema pallidum infections among blood donors in Offinso-North District, Ghana: a nine-year retrospective, cross-sectional study. African Health Sciences, 22(1), 465–474. doi:10.4314/ahs.v22i1.55.

Jing, W., Zhao, S., Liu, J., & Liu, M. (2020). ABO blood groups and hepatitis B virus infection: A systematic review and meta-analysis. BMJ Open, 10(1), 34114. doi:10.1136/bmjopen-2019-034114.

Nkansah, C., Serwaa, D., Osei-Boakye, F., & Owusu-Ampomah, R. (2020). Seroprevalence and trend of hepatitides among blood donors in a district hospital in Ghana: a nine-year retrospective, descriptive cross-sectional study. Journal of Immunoassay and Immunochemistry, 41(1), 71–83. doi:10.1080/15321819.2019.1682601.

Genc, O. (2017). Hepatitis B virus infection and ABO/Rh blood groups. International Journal of Research in Medical Sciences, 5(9), 3782. doi:10.18203/2320-6012.ijrms20173949.

Arac, E., Solmaz, I., & Samanci, S. (2019). ABO and Rh blood groups frequency in men, women and neonates in Diyarbakir province. Annals of Medical Research, 26(12), 2876. doi:10.5455/annalsmedres.2019.09.538.


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DOI: 10.28991/SciMedJ-2023-05-02-03

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Copyright (c) 2023 Felix Osei-Boakye, Felix Osei-Boakye, Nicholas Agyepong, Charles Nkansah, Abdul-Razak Saasi, Dorcas Serwaa, Mark Danquah, Kwesi Kattah, Mohammed Khadija, Fati Salifu, Andrea Owusu Antwi